Triphenylphosphonium-functionalized dimeric BODIPY-based nanoparticles for mitochondria-targeting photodynamic therapy

Author:

Kim Chanwoo1ORCID,Mai Duy Khuong2,Lee Joomin3,Jo Jinwoong1,Kim Soyeon1,Badon Isabel Wen24,Lim Jong Min5ORCID,Kim Ho-Joong2,Yang Jaesung1ORCID

Affiliation:

1. Department of Chemistry, Yonsei University, Wonju, Gangwon 26493, Korea

2. Department of Chemistry, Chosun University, Gwangju 61452, Korea

3. Department of Food and Nutrition, Chosun University, Gwangju 61452, Korea

4. Department of Life Sciences, Chung-Ang University, Seoul 06974, Korea

5. Department of Chemistry, Kyungpook National University, Daegu 41566, Korea

Abstract

This study reports the synthesis, characterization, and photodynamic therapy activity of two orthogonal BODIPY dimers functionalized with TPP cations for mitochondrial targeting.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

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