Current advances of carbene-mediated photoaffinity labeling in medicinal chemistry-Reference-Cited by-同舟云学术

Current advances of carbene-mediated photoaffinity labeling in medicinal chemistry

Published:2018 Issue:51 Volume:8 Page:29428-29454
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ge Sha-Sha¹²³⁴⁵,Chen Biao¹²³⁴⁵,Wu Yuan-Yuan¹²³⁴⁵,Long Qing-Su¹²³⁴⁵,Zhao Yong-Liang¹²³⁴⁵,Wang Pei-Yi¹²³⁴⁵,Yang Song¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering

2. Key Laboratory of Green Pesticide and Agricultural Bioengineering

3. Ministry of Education

4. Center for R&D of Fine Chemicals of Guizhou University

5. Guiyang 550025

Abstract

Photoaffinity labeling (PAL) in combination with a chemical probe to covalently bind its target upon UV irradiation has demonstrated considerable promise in drug discovery for identifying new drug targets and binding sites.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA03538E

Reference219 articles.

1. Recent Progress in Diazirine‐Based Photoaffinity Labeling

2. Photocrosslinkers illuminate interactions in living cells

3. Photoaffinity labeling in target- and binding-site identification

4. Photoaffinity labeling studies of the carbohydrate-binding proteins with different affinities

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