Inhibition of the Ras/ERK1/2 pathway contributes to the protective effect of ginsenoside Re against intimal hyperplasia-Reference-Cited by-同舟云学术

Inhibition of the Ras/ERK1/2 pathway contributes to the protective effect of ginsenoside Re against intimal hyperplasia

Published:2021 Issue:15 Volume:12 Page:6755-6765
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Gao Chenying¹²³⁴⁵,Zhang Kaina¹²³⁴⁵,Liang Fanfan¹²³⁴⁵,Ma Wenzhuo¹²³⁴⁵,Jiang Xixi¹²³⁴⁵,Wang Hongying¹²³⁴⁵,Zhan Heqin¹⁶⁷⁸⁵,Sonkoly Enikö⁹¹⁰¹¹¹²¹³,Hu Hao¹²³⁴⁵,Zhao Zhenghang¹²³⁴⁵^ORCID

Affiliation:

1. Department of Pharmacology

2. School of Basic Medical Sciences

3. Xi'an Jiaotong University

4. Xi'an

5. China

6. College of Pharmacy

7. Xinxiang Medical University

8. Xinxiang

9. Molecular Dermatology Research Group

10. Unit of Dermatology and Venereology

11. Centre for Molecular Medicine (CMM)

12. Department of Medicine

13. Karolinska Institute

Abstract

Re was shown to inhibit vascular injury-induced neointimal thickening probably by promoting VSMC apoptosis and inhibiting autophagy via suppression of the Ras/MEK/ERK1/2 signalling pathway.

Funder

Natural Science Foundation of Shaanxi Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO00015B

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