PEG-grafted arsenic trioxide-loaded mesoporous silica nanoparticles endowed with pH-triggered delivery for liver cancer therapy-Reference-Cited by-同舟云学术

PEG-grafted arsenic trioxide-loaded mesoporous silica nanoparticles endowed with pH-triggered delivery for liver cancer therapy

Published:2023 Issue:15 Volume:11 Page:5301-5319
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Jiang Liangdi¹^ORCID,Wang Xuerui¹,Raza Faisal¹^ORCID,Zhong Hongyu¹,Su Jing¹^ORCID,Yuan Wei-En²^ORCID,Qiu Mingfeng¹^ORCID

Affiliation:

1. School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China

2. Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China

Abstract

A pH-responsive nanoplatform (PEG-MSN@ATO) was fabricated. It can accumulate more to the tumor and achieve pH-triggered ATO release in the tumor microenvironment, exerting the anti-liver cancer effect through multiple mechanisms of ATO.

Funder

National Natural Science Foundation of China

National Science and Technology Major Project

Science and Technology Commission of Shanghai Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D3BM00555K

Reference84 articles.

1. Immunotherapy in hepatocellular carcinoma: How does underlying liver disease influence therapeutic strategy and outcomes?