Synthesis of imidazoles via cascade reaction of nitroallylic acetates with amidines and studies on their trypanocidal activity-Reference-Cited by-同舟云学术

Synthesis of imidazoles via cascade reaction of nitroallylic acetates with amidines and studies on their trypanocidal activity

Published:2015 Issue:7 Volume:13 Page:1996-2000
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Kumar Tarun¹²³,Verma Deepti¹²³,Menna-Barreto Rubem F. S.⁴⁵⁶,Valença Wagner O.⁷⁸⁹¹⁰⁶,da Silva Júnior Eufrânio N.⁷⁸⁹¹⁰⁶,Namboothiri Irishi N. N.¹²³

Affiliation:

1. Indian Institute of Technology Bombay

2. Mumbai 400 076

3. India

4. Oswaldo Cruz Institute

5. Rio de Janeiro

6. Brazil

7. Institute of Exact Sciences

8. Department of Chemistry

9. Federal University of Minas Gerais

10. Belo Horizonte

Abstract

Functionalized imidazoles derived from nitroallylic acetates and amidines exhibit potent activity against T. cruzi, the etiological agent of Chagas disease.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C4OB02561J

Reference71 articles.

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2. K. Hofmann , in The Chemistry of Heterocyclic Compounds: Imidazole and Its Derivatives, Part I, ed. A. Weissberger, Wiley Interscience, New York, 1953

3. A Review on Biological Activity of Imidazole and Thiazole Moieties and their Derivatives

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