Apigenin protects mice against 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestasis-Reference-Cited by-同舟云学术

Apigenin protects mice against 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestasis

Published:2021 Issue:5 Volume:12 Page:2323-2334
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zheng Shihong¹²³⁴⁵,Cao Peichang¹²³⁴⁵,Yin Zequn¹²³⁴⁵,Wang Xuerui¹²³⁴⁵,Chen Yuanli¹²³⁴⁵^ORCID,Yu Maoyun⁶⁷⁸⁵,Xu Baocai¹²³⁴⁵,Liao Chenzhong¹²³⁴⁵,Duan Yajun¹²³⁴⁵,Zhang Shuang¹²³⁴⁵,Han Jihong¹²³⁴⁵,Yang Xiaoxiao¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes

2. College of Food and Biological Engineering

3. Hefei University of Technology

4. Hefei

5. China

6. School of Biological and Pharmaceutical Engineering

7. West Anhui University

8. Lu'an

Abstract

Apigenin prevented the DDC-induced abnormal lipid metabolism, liver damage and liver fibrosis by reducing inflammation and oxidative stress. Apigenin might be a potential drug for the treatment of cholestatic liver diseases.

Funder

International Science and Technology Cooperation Programme

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Anhui Provincial Key Research and Development Plan

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D0FO02910F