6-Gingerol ameliorates ulcerative colitis by inhibiting ferroptosis based on the integrative analysis of plasma metabolomics and network pharmacology-Reference-Cited by-同舟云学术

6-Gingerol ameliorates ulcerative colitis by inhibiting ferroptosis based on the integrative analysis of plasma metabolomics and network pharmacology

Published:2024 Issue:11 Volume:15 Page:6054-6067
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Li Wenwen¹,Zhang Yun¹,Wang Quyi¹,Wang Yu¹,Fan Yuwen¹,Shang Erxin¹,Jiang Shu¹^ORCID,Duan Jinao¹^ORCID

Affiliation:

1. Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing, 210023, PR China

Abstract

An integrated strategy of plasma metabolomics, network pharmacology, experimental verification, and molecular docking was used to elucidate that ferroptosis is involved in the amelioration of colitis by 6-G.

Funder

National Natural Science Foundation of China

Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D4FO00952E

Reference55 articles.

1. Ulcerative Colitis in Adults

2. Update on the epidemiology of inflammatory bowel disease in Asia: where are we now?

3. Implications of the changing epidemiology of inflammatory bowel disease in a changing world

4. Breaking the therapeutic ceiling in drug development in ulcerative colitis

5. Ginger ( Zingiber officinale Rosc.) and its bioactive components are potential resources for health beneficial agents

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