A novel amplified double-quenching aptasensor for cocaine detection based on split aptamer and silica nanoparticles-Reference-Cited by-同舟云学术

A novel amplified double-quenching aptasensor for cocaine detection based on split aptamer and silica nanoparticles

Published:2018 Issue:26 Volume:10 Page:3232-3236
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Abnous Khalil¹²³⁴⁵^ORCID,Danesh Noor Mohammad⁶⁴⁵,Ramezani Mohammad¹²³⁴⁵,Taghdisi Seyed Mohammad⁷²³⁴⁵^ORCID,Emrani Ahmad Sarreshtehdar⁸⁹³⁴⁵

Affiliation:

1. Pharmaceutical Research Center

2. Pharmaceutical Technology Institute

3. Mashhad University of Medical Sciences

4. Mashhad

5. Iran

6. Research Institute of Sciences and New Technology

7. Targeted Drug Delivery Research Center

8. Cardiovascular Research Center

9. School of Medicine

Abstract

Herein, a sensitive and rapid fluorescent aptasensor was developed for the detection of cocaine as an illicit drug, based on an amplification strategy involving the use of silica nanoparticles coated with streptavidin (SNPs), double quenching of FAM fluorophore and cocaine split aptamer.

Funder

Mashhad University of Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/AY/C8AY00755A

Reference26 articles.

1. A holographic sensor based on a biomimetic affinity ligand for the detection of cocaine

2. Polymer platforms for selective detection of cocaine in street samples adulterated with levamisole

3. A novel colorimetric biosensor based on non-aggregated Au@Ag core–shell nanoparticles for methamphetamine and cocaine detection