Sub-100 nm patterning of TiO2 film for the regulation of endothelial and smooth muscle cell functions

Author:

Muhammad R.12345,Lim S. H.45678,Goh S. H.12345,Law J. B. K.4567,Saifullah M. S. M.4567,Ho G. W.823,Yim E. K. F.12392

Affiliation:

1. Department of Biomedical Engineering

2. National University of Singapore

3. Singapore 117576, Republic of Singapore

4. Institute of Materials Research and Engineering

5. A*STAR (Agency for Science

6. Technology and Research)

7. Singapore 117602, Republic of Singapore

8. Department of Electrical and Computer Engineering

9. Mechanobiology Institute

Abstract

A sub-100 nm nano-imprinted TiO2 layer significantly inhibited the proliferation of SMCs and increased the proliferation of HUVECs. Focal adhesions size, density and distribution were significantly modulated by nano-imprinted TiO2.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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