Site-specific 2D IR spectroscopy: a general approach for the characterization of protein dynamics with high spatial and temporal resolution-Reference-Cited by-同舟云学术

Site-specific 2D IR spectroscopy: a general approach for the characterization of protein dynamics with high spatial and temporal resolution

Published:2019 Issue:2 Volume:21 Page:780-788
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Ramos Sashary¹²³⁴⁵^ORCID,Horness Rachel E.¹²³⁴⁵,Collins Jessica A.¹²³⁴⁵,Haak David⁵⁶⁴,Thielges Megan C.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Indiana University

3. Bloomington

4. USA

5. Indiana University School of Medicine

6. Indianapolis

Abstract

The conformational heterogeneity and dynamics of protein side chains contribute to function, but investigating exactly how is hindered by experimental challenges arising from the fast timescales involved and the spatial heterogeneity of protein structures.

Funder

National Institute of General Medical Sciences

Division of Molecular and Cellular Biosciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CP/C8CP06146G

Reference52 articles.

1. NMR Probes of Molecular Dynamics: Overview and Comparison with Other Techniques

2. Dynamically driven protein allostery