On-chip integration of organic synthesis and HPLC/MS analysis for monitoring stereoselective transformations at the micro-scale-Reference-Cited by-同舟云学术

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On-chip integration of organic synthesis and HPLC/MS analysis for monitoring stereoselective transformations at the micro-scale

Published:2017 Issue:1 Volume:17 Page:76-81
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Heiland Josef J.¹²³⁴,Warias Rico¹²³⁴,Lotter Carsten¹²³⁴,Mauritz Laura¹²³⁴,Fuchs Patrick J. W.⁵²³⁴,Ohla Stefan¹²³⁴,Zeitler Kirsten⁵²³⁴^ORCID,Belder Detlev¹²³⁴

Affiliation:

1. Institute of Analytical Chemistry

2. University of Leipzig

3. D-04103 Leipzig

4. Germany

5. Institute of Organic Chemistry

Abstract

Seamless on-chip integration of a micro reaction unit and an HPLC functionality coupled to MS allows to study stereo selective chemical transformations at the microscale.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2017/LC/C6LC01217E

Reference61 articles.

1. Continuous process technology: a tool for sustainable production

2. Expanding the toolbox of asymmetric organocatalysis by continuous-flow process

3. Synthesis of 5-Substituted 1H-Tetrazoles from Nitriles and Hydrazoic Acid by Using a Safe and Scalable High-Temperature Microreactor Approach

4. Microfluidics in Inorganic Chemistry

5. The integration of flow reactors into synthetic organic chemistry

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