Immobilized enzymes: understanding enzyme – surface interactions at the molecular level
Author:
Affiliation:
1. Department of Chemistry
2. University of Michigan
3. Ann Arbor
4. USA
5. Department of Biological Chemistry
Abstract
Interactions between immobilized enzymes and supporting surfaces are complex and context-dependent and can significantly alter enzyme structure, stability and activity.
Funder
Defense Threat Reduction Agency
Army Research Office
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB01880K
Reference106 articles.
1. Water structure at solid surfaces and its implications for biomolecule adsorption
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4. Chemical Modification in the Design of Immobilized Enzyme Biocatalysts: Drawbacks and Opportunities
5. Conformational changes of enzymes upon immobilisation
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