Straightforward access to densely substituted chiral succinimides through enantioselective organocatalyzed Michael addition of α-alkyl-cyclic ketones to maleimides

Abstract

A simple, cheap and unchanged organocatalytic system provides efficient access to densely substituted chiral succinimides bearing QCC–TCC vicinal stereocenters from unreactive α-alkyl cyclic ketones and maleimides.