In vivo toxicity evaluation of two polyoxotungstates with potential antidiabetic activity using Wistar rats as a model system

Author:

Dinčić Marko1234,Čolović Mirjana B.5634ORCID,Sarić Matutinović Marija78934,Ćetković Mila10234,Kravić Stevović Tamara10234,Mougharbel Ali S.11121314,Todorović Jasna1234,Ignjatović Svetlana78934,Radosavljević Branimir1523164,Milisavljević Milan17234,Kortz Ulrich11121314ORCID,Krstić Danijela Z.1523164ORCID

Affiliation:

1. Institute of Pathological Physiology

2. Faculty of Medicine

3. University of Belgrade

4. Serbia

5. Department of Physical Chemistry

6. “Vinča” Institute of Nuclear Sciences

7. Department for Medical Biochemistry

8. Laboratory for Medical Biochemical Analysis

9. Faculty of Pharmacy

10. Institute of Histology and Embryology

11. Department of Life Sciences and Chemistry

12. Jacobs University

13. 28759 Bremen

14. Germany

15. Institute of Medical Chemistry

16. Belgrade

17. Institute of Anatomy

Abstract

Study of the in vivo hypoglycemic effect, hepatotoxicity and nephrotoxicity of a donut-shaped polyanion salt (NH4)14[Na@P5W30O110]·31H2O {NaP5W30} and its Ag-containing derivative K14[Ag@P5W30O110]·22H2O·6KCl {AgP5W30}.

Funder

Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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