Aryl-to-alkyl radical relay Heck reaction of amides with vinyl arenes-Reference-Cited by-同舟云学术

Aryl-to-alkyl radical relay Heck reaction of amides with vinyl arenes

Published:2023 Issue:13 Volume:14 Page:3580-3586
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Du Yu-jia¹,Sheng Xia-xin¹,Li Jun-hua¹^ORCID,Chen Jia-ming¹,Yang Sen¹,Chen Ming¹^ORCID

Affiliation:

1. Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, School of Petrochemical Engineering, Changzhou University, 21 Gehu Road, Changzhou, 213164, China

Abstract

Herein, a photo-induced palladium catalyzed aryl-to-alkyl radical relay Heck reaction at α-C(sp3)–H site of amide has been developed. This method is scalable and operationally simple. Mechanistic studies reveal the radical nature of this transformation.

Funder

Changzhou University

National Natural Science Foundation of China

Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology Department

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D2SC06852D

Reference57 articles.

1. Palladium-catalyzed vinylic hydrogen substitution reactions with aryl, benzyl, and styryl halides