An improved structure-switch aptamer-based fluorescent Pb2+ biosensor utilizing the binding induced quenching of AMT to G-quadruplex

Author:

Geng Fenghua12345ORCID,Wang Dandan6789,Feng Li12345,Li Guixin6789,Xu Maotian106111213ORCID

Affiliation:

1. National Engineering Research Center of Coal Preparation and Purification

2. Key Laboratory of Coal Processing and Efficient Utilization of Ministry of Education

3. School of Chemical Engineering and Technology

4. China University of Mining & Technology

5. Xuzhou

6. College of Chemistry and Chemical Engineering

7. Xinjiang Normal University

8. Urumqi

9. China

10. Henan Key Laboratory of Biomolecular Recognition and Sensing

11. Henan Joint International Research Laboratory of Chemo/Biosensing and Early Diagnosis of Major Diseases

12. Shangqiu Normal University

13. Shangqiu

Abstract

Binding-induced quenching of AMT to G-quadruplex is used for the first time to design an improved fluorescent Pb2+ aptasensor.

Funder

National Natural Science Foundation of China

Innovation Scientists and Technicians Troop Construction Projects of Henan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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