Metal catalyst free one-pot synthesis of 2-arylbenzimidazoles from α-aroylketene dithioacetals-Reference-Cited by-同舟云学术

Metal catalyst free one-pot synthesis of 2-arylbenzimidazoles from α-aroylketene dithioacetals

Published:2014 Issue:23 Volume:4 Page:12028-12036
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Dhanalakshmi Pandi¹²³⁴,Thimmarayaperumal Solaimalai¹²³⁴,Shanmugam Sivakumar¹²³⁴

Affiliation:

1. Department of Organic Chemistry

2. School of Chemistry

3. Madurai Kamaraj University

4. Madurai 625021, India

Abstract

An efficient green synthetic approach has been developed towards the synthesis of 2-aryl substituted benzimidazoles 4 from α-aroylketene dithioacetals (AKDTAs) 1 and phenylenediamine (OPD) 2.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C3RA47761D

Reference62 articles.

1. Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors

2. Identification of 2-arylbenzimidazoles as potent human histamine H4 receptor ligands

3. In-vitro susceptibility of Giardia lamblia to albendazole, mebendazole and other chemotherapeutic agents

4. Cardiotonic agents. Synthesis and cardiovascular properties of novel 2-arylbenzimidazoles and azabenzimidazoles

5. Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of minimal DNA-intercalating agents which may not act via topoisomerase II

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