Selenium enriched Bacillus subtilis yb-1114246 activated the TLR2–NF-κB1 signaling pathway to regulate chicken intestinal β-defensin 1 expression

Author:

Yang Jiajun12345,Wang Jing12346,Huang Kehe6784,Zhu Mengling1234,Liu Qinxing1234,Liu Guofang1234,Chen Fu59104,Zhang Hao59104ORCID,Qin Shunyi111213144

Affiliation:

1. School of Animal Science and Veterinary Medicine

2. Jiangsu Vocational College of Agriculture and Forestry

3. Jurong

4. China

5. College of Animal Science and Technology

6. College of Veterinary Medicine

7. Nanjing Agricultural University

8. Nanjing

9. Chinese Agricultural University

10. Beijing

11. Key Laboratory of Agricultural Animal Breeding and Healthy Breeding of Tianjin

12. College of Animal Science and Veterinary Medicine

13. Tianjin Agricultural University

14. Tianjin

Abstract

B. subtilis yb-111246 was recognized by TLR2 in chicken intestine and present the signal to MyD88. The potential signaling pathway of SEBS was proposed to be TLR2–MyD88–NF-κB1, upregulated the expression of BD1.

Funder

China Agricultural Research System

Major Scientific and Technological Innovation Project of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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