The use of an <i>in vitro</i> fecal fermentation model to uncover the beneficial role of omega-3 and punicic acid in gut microbiota alterations induced by a Western diet-Reference-Cited by-同舟云学术

The use of an in vitro fecal fermentation model to uncover the beneficial role of omega-3 and punicic acid in gut microbiota alterations induced by a Western diet

Published:2024 Issue:11 Volume:15 Page:6095-6117
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Salsinha Ana Sofia¹²^ORCID,Cima André¹^ORCID,Araújo-Rodrigues Helena¹²^ORCID,Viana Sofia³⁴⁵,Reis Flávio³⁴^ORCID,Coscueta Ezequiel R.¹^ORCID,Rodríguez-Alcalá Luis Miguel¹^ORCID,Relvas João B.²⁶,Pintado Manuela¹^ORCID

Affiliation:

1. Universidade Católica Portuguesa, CBQF – Centro de Biotecnologia e Química Fina –Laboratório Associado, Escola Superior de Biotecnologia, Rua de Diogo Botelho, 1327, 4169-005 Porto, Portugal

2. Instituto de Investigação e Inovação em Saúde and Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto – Rua Alfredo Allen, 208, 4200-135 Porto, Portugal

3. Coimbra Institute of Clinical and Biomedical Research (iCBR), Faculty of Medicine and Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal

4. Clinical Academic Center of Coimbra, Coimbra, Portugal

5. Instituto Politécnico de Coimbra, Escola Superior de Tecnologia da Saúde de Coimbra, Rua 5 de Outubro – S. Martinho Bispo, Apartado 7006, 3046-854 Coimbra, Portugal

6. Departmento de Biomedicina, Faculdade de Medicina da Universidade do Porto (FMUP), 4200-319 Porto, Portugal

Abstract

Caecal samples from rats on a Western diet were fermented in vitro to assess Fish and Pomegranate oil's impact on gut microbiota. Fish oil + Pomegranate oil raised α-diversity, butyrate, acetate, and GABA in the Western diet group.

Funder

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D4FO00727A

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