A strategy for orthogonal deubiquitination using a bump-and-hole approach-Reference-Cited by-同舟云学术

A strategy for orthogonal deubiquitination using a bump-and-hole approach

Published:2023 Issue:11 Volume:4 Page:879-883
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Suzuki Takumi¹,Utsugi Yuki¹,Yamanaka Satoshi²,Takahashi Hirotaka²,Sato Yusuke³⁴,Sawasaki Tatsuya²,Miyamae Yusaku⁵^ORCID

Affiliation:

1. Master's/Doctoral Program in Life Science Innovation, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, 305-8572, Japan

2. Division of Cell-Free Science, Proteo-Science Center, Ehime University, Matsuyama, Ehime, 790-8577, Japan

3. Center for Research on Green Sustainable Chemistry, Tottori University, Tottori 680-8552, Japan

4. Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, Tottori 680-8552, Japan

5. Institute of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki, 305-8572, Japan

Abstract

We established orthogonal deubiquitination, which enables us to selectively observe a single type of deubiquitinating enzyme activity in living cells.

Funder

Ministry of Education, Culture, Sports, Science and Technology

Japan Society for the Promotion of Science

Takeda Science Foundation

Japan Agency for Medical Research and Development

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CB/D3CB00095H

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