Cyclotrimetaphosphate-assisted ruthenium catalyst for the hydration of nitriles and oxidation of primary amines to amides under aerobic conditions in water

Author:

Chouhan Kishor Kumar1,Chowdhury Deep1,Mukherjee Arup1ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology Bhilai, GEC Campus, Sejbahar, Raipur, Chhattisgarh 492015, India

Abstract

A simple ruthenium-based catalytic system is presented for the hydration of nitriles and oxidation of primary amines to amides under ambient conditions in water. Controlled experiments were performed to understand the mechanism.

Funder

Council of Scientific and Industrial Research, India

University Grants Commission

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference101 articles.

1. The Amide Linkage: Structural Significance in Chemistry, Biochemistry, and Materials Science , ed. A. Greenberg , C. M. Breneman and J. F. Liebman , Wiley , 2000

2. Chemical Synthesis of Natural Product Peptides:  Coupling Methods for the Incorporation of Noncoded Amino Acids into Peptides

3. Synthetic polypeptides for biomedical applications

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