Constructing spirooxindoles from non-oxindole precursors: a one-pot nitro-reduction/double lactamization approach to spiro[indoline-3,3′-quinoline]-2,2′-diones-Reference-Cited by-同舟云学术

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Constructing spirooxindoles from non-oxindole precursors: a one-pot nitro-reduction/double lactamization approach to spiro[indoline-3,3′-quinoline]-2,2′-diones

Published:2024 Issue: Volume: Page:
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Chouhan Raju¹,Gogoi Abhijit¹^ORCID,Das Sajal Kumar¹^ORCID

Affiliation:

1. Department of Chemical Sciences, Tezpur University, Napaam, Tezpur, Assam, India 784028

Abstract

Spiro[indoline-3,3′-quinoline]-2,2′-diones bearing two free amide NH moieties have been synthesized for the first time via a one-pot nitro-reduction/double lactamization approach.

Funder

Science and Engineering Research Board

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB01178C

Reference54 articles.

1. Privileged scaffolds for library design and drug discovery

2. L.Yet , Privileged Structures in Drug Discovery: Medicinal Chemistry and Synthesis , Wiley , 2018

3. An overview of spirooxindole as a promising scaffold for novel drug discovery

4. Spiro-oxindoles as a Promising Class of Small Molecule Inhibitors of p53–MDM2 Interaction Useful in Targeted Cancer Therapy

5. Therapeutic Potential of Spirooxindoles as Antiviral Agents

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