Practical synthesis of allylic amines <i>via</i> nickel-catalysed multicomponent coupling of alkenes, aldehydes, and amides-Reference-Cited by-同舟云学术

Practical synthesis of allylic amines via nickel-catalysed multicomponent coupling of alkenes, aldehydes, and amides

Published:2023 Issue:32 Volume:14 Page:8644-8650
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Xiao Wei-Guo¹,Xuan Bin¹,Xiao Li-Jun¹^ORCID,Zhou Qi-Lin¹^ORCID

Affiliation:

1. State Key Laboratory, Institute of Elemento-Organic Chemistry, College of Chemistry, Frontiers Science Center for New Organic Matter, Nankai University, Tianjin 300071, China

Abstract

A practical and efficient protocol is reported for synthesizing valuable allylic amines via a catalytic multicomponent coupling reaction of alkenes, aldehydes, and amides using nickel and Lewis acid catalysts.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC03233G

Reference79 articles.

1. Allylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide Isosteres