Chitooligosaccharides alleviate hepatic fibrosis by regulating the polarization of M1 and M2 macrophages-Reference-Cited by-同舟云学术

Chitooligosaccharides alleviate hepatic fibrosis by regulating the polarization of M1 and M2 macrophages

Published:2022 Issue:2 Volume:13 Page:753-768
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Liu Peng¹,Li Heng¹^ORCID,Gong Jinsong¹,Geng Yan¹,Jiang Min¹,Xu Hongyu²,Xu Zhenghong²^ORCID,Shi Jinsong¹^ORCID

Affiliation:

1. Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, China

2. National Engineering Laboratory for Cereal Fermentation Technology, School of Biotechnology, Jiangnan University, Wuxi 214122, China

Abstract

Chitooligosaccharide (COS) ameliorated hepatic fibrosis, possibly by regulating the M1 and M2 polarization of the liver macrophages, which was reflected in the modulation of the JAK1/STAT6 and JAK2/STAT1 pathways.

Funder

Key Research and Development Program of Ningxia

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D1FO03768D

Reference57 articles.

1. Cytotherapy with M1-polarized macrophages ameliorates liver fibrosis by modulating immune microenvironment in mice

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4. Liver inflammation and fibrosis

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