Multifunctional antibiotics-free hydrogel dressings with self-regulated nitric oxide-releasing kinetics for improving open wound healing

Author:

Liu Yuan1,Tan Lu1,Huang Yan1,Chen Maohua1,Li Menghuan2,Cai Kaiyong1ORCID,Luo Zhong2ORCID,Hu Yan1ORCID

Affiliation:

1. Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China

2. School of Life Science, Chongqing University, Chongqing 400044, China

Abstract

In this study, an antibiotics-free hydrogel with self-regulated nitric oxide release kinetics was developed, which could eliminate bacteria in early stages of wound healing while facilitating wound closure at later stages.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Chongqing

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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