Diagnosis of traumatic brain injury using miRNA signatures in nanomagnetically isolated brain-derived extracellular vesicles-Reference-Cited by-同舟云学术

Diagnosis of traumatic brain injury using miRNA signatures in nanomagnetically isolated brain-derived extracellular vesicles

Published:2018 Issue:23 Volume:18 Page:3617-3630
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Ko J.¹²³⁴^ORCID,Hemphill M.¹²³⁴,Yang Z.¹²³⁴,Sewell E.¹²³⁴,Na Y. J.⁵⁶⁷⁸⁹,Sandsmark D. K.¹⁰¹¹³⁴,Haber M.¹⁰¹¹³⁴,Fisher S. A.¹²²³⁴,Torre E. A.¹²³⁴,Svane K. C.¹³¹⁴¹⁵⁴,Omelchenko A.¹³¹⁴¹⁵⁴,Firestein B. L.¹³¹⁴¹⁵⁴^ORCID,Diaz-Arrastia R.¹⁰¹¹³⁴,Kim J.¹²²³⁴¹⁶,Meaney D. F.¹²³⁴¹⁷,Issadore D.¹²³⁴¹⁸^ORCID

Affiliation:

1. Department of Bioengineering

2. University of Pennsylvania

3. Philadelphia

4. USA

5. Department of Medicine

6. Division of Nephrology

7. College of Physicians and Surgeons

8. Columbia University

9. New York

10. Department of Neurology

11. University of Pennsylvania Perelman School of Medicine

12. Department of Biology

13. Department of Cell Biology and Neuroscience

14. Rutgers

15. the State University of New Jersey

16. Department of Computer and Information Science

17. Department of Neurosurgery

18. Department of Electrical and Systems Engineering

Abstract

We developed a platform to isolate brain-derived extracellular vesicles and measure their miRNA biomarkers to classify specific states of traumatic brain injury.

Funder

New Jersey Commission on Brain Injury Research

American Cancer Society

National Science Foundation

Allen Foundation

National Institutes of Health

Pennsylvania Department of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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