Sparganin A alleviates blood stasis syndrome and its key targets by molecular docking-Reference-Cited by-同舟云学术

Sparganin A alleviates blood stasis syndrome and its key targets by molecular docking

Published:2019 Issue:65 Volume:9 Page:37978-37985
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Xian Minghua¹²³⁴⁵^ORCID,Ji Sulong¹²³⁴⁵,Chen Chen¹²³⁴⁵,Liang Shengwang¹²³⁴⁵,Wang Shumei⁵²³⁴⁶

Affiliation:

1. School of Traditional Chinese Medicine

2. Guangdong Pharmaceutical University

3. Guangzhou 510006

4. China

5. Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM

6. Engineering & Technology Research Center for Chinese Materia Medica Quality of the Universities of Guangdong Province

Abstract

Sparganin A (SA), a promising drug to control coagulation in blood stasis syndrome, was successfully isolated. In an acute blood stasis model, the concentrations of TXB2, PAI-1, FIB, ET-1 were measured. Molecular docking was employed to identify the key targets of SA.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA06329C

Reference29 articles.

1. Herb pair Danggui-Honghua: mechanisms underlying blood stasis syndrome by system pharmacology approach

2. Comparative Analysis of Compatibility Effects on Invigorating Blood Circulation for Cyperi Rhizoma Series of Herb Pairs Using Untargeted Metabolomics

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4. Bleeding associated with the management of acute coronary syndromes

5. Stroke Mechanisms

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