Highly sensitive ligand-binding assays in pre-clinical and clinical applications: immuno-PCR and other emerging techniques-Reference-Cited by-同舟云学术

Highly sensitive ligand-binding assays in pre-clinical and clinical applications: immuno-PCR and other emerging techniques

Published:2015 Issue:18 Volume:140 Page:6175-6194
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Spengler Mark¹²³,Adler Michael¹²³,Niemeyer Christof M.⁴⁵⁶⁷³

Affiliation:

1. Chimera Biotec GmbH

2. D-44227 Dortmund

3. Germany

4. Karlsruhe Institute of Technologie (KIT)

5. Institute for Biological Interfaces (IBG-1)

6. Biomolecular Micro- and Nanostructures

7. D-76344 Eggenstein-Leopoldshafen

Abstract

Emerging state-of-the-art ligand-binding assay technologies for pharmaceutical sample testing are surveyed, which reveal enhanced analytical sensitivity over classical ELISA formats.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/AN/C5AN00822K

Reference260 articles.

1. Bioanalysis of antibody–drug conjugates: American Association of Pharmaceutical Scientists Antibody–Drug Conjugate Working Group position paper

2. Antibody Conjugate Therapeutics: Challenges and Potential

3. Shifting paradigms: biopharmaceuticals versus low molecular weight drugs

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