AQP2 as a target of lycopene protects against atrazine-induced renal ionic homeostasis disturbance-Reference-Cited by-同舟云学术

AQP2 as a target of lycopene protects against atrazine-induced renal ionic homeostasis disturbance

Published:2021 Issue:11 Volume:12 Page:4855-4863
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Guo Jian-Ying¹²³⁴,Lin Jia¹²³⁴⁵,Huang Yue-Qiang¹²³⁴,Talukder Milton¹²³⁴⁶,Yu Lei¹²³⁴,Li Jin-Long¹²³⁴⁷^ORCID

Affiliation:

1. College of Veterinary Medicine

2. Northeast Agricultural University

3. Harbin

4. P. R. China

5. Hubei Key Laboratory of Animal Nutrition and Feed Science

6. Department of Physiology and Pharmacology

7. Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment

Abstract

This study shows that atrazine exposure can lead to nephrotoxicity by interfering with ion homeostasis. Lycopene maintains ion homeostasis by regulating the expression of AQPs and the activity of ATPase, and antagonizes the nephrotoxicity induced by atrazine.

Funder

Excellent Youth Foundation of Heilongjiang Province of China

National Natural Science Foundation of China

Earmarked Fund for China Agriculture Research System

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D0FO03214J

Reference48 articles.

1. Characterization of S -Triazine Herbicide Metabolism by a Nocardioides sp. Isolated from Agricultural Soils