The cytochromeb5CybE is regulated by iron availability and is crucial for azole resistance inA. fumigatus-Reference-Cited by-同舟云学术

The cytochromeb5CybE is regulated by iron availability and is crucial for azole resistance inA. fumigatus

Published:2017 Issue:11 Volume:9 Page:1655-1665
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Misslinger Matthias¹²³⁴⁵^ORCID,Gsaller Fabio⁶⁷⁸⁹¹⁰^ORCID,Hortschansky Peter¹¹¹²¹³¹⁴,Müller Christoph¹⁵¹⁶¹⁷¹⁸¹⁴,Bracher Franz¹⁵¹⁶¹⁷¹⁸¹⁴,Bromley Michael J.⁶⁷⁸⁹¹⁰,Haas Hubertus¹²³⁴⁵^ORCID

Affiliation:

1. Division of Molecular Biology

2. Biocenter

3. Medical University of Innsbruck

4. 6020 Innsbruck

5. Austria

6. Manchester Fungal Infection Group

7. Institute of Inflammation and Repair

8. University of Manchester

9. Manchester

10. UK

11. Department of Molecular and Applied Microbiology

12. Leibniz Institute for Natural Product Research and Infection Biology (HKI)

13. Jena

14. Germany

15. Department of Pharmacy

16. Center for Drug Research

17. Ludwig-Maximilians-University Munich

18. Munich

Abstract

Cytochrome P450 enzymes (P450) play essential roles in redox metabolism in all domains of life including detoxification reactions and sterol biosynthesis.

Funder

Deutsche Forschungsgemeinschaft

Austrian Science Fund

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MT/C7MT00110J

Reference59 articles.

1. Comparison of xenobiotic-metabolising human, porcine, rodent, and piscine cytochrome P450

2. Versatile biocatalysis of fungal cytochrome P450 monooxygenases