OWL2: a molecular beacon-based nanostructure for highly selective detection of single-nucleotide variations in folded nucleic acids-Reference-Cited by-同舟云学术

OWL2: a molecular beacon-based nanostructure for highly selective detection of single-nucleotide variations in folded nucleic acids

Published:2023 Issue:12 Volume:15 Page:5735-5742
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Mueller Brittany L.¹^ORCID,Liberman Mark J.¹,Kolpashchikov Dmitry M.¹²³^ORCID

Affiliation:

1. Chemistry Department, University of Central Florida, 4000 Central Florida Blvd., Orlando, FL 32816, USA

2. Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, USA

3. National Center for Forensic Science, University of Central Florida, Orlando, FL, USA

Abstract

OWL2 sensor uses T2 and T4 arms for unwinding folded analytes, short P-strand for specific recognition of single base variations and an analyte-independent universal molecular beacon (UMB) probe for cost efficient analysis of any ssDNA or RNA.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NR/D2NR05590B

Reference44 articles.

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4. Detecting pathogenic variants in autoimmune diseases using high‐throughput sequencing

5. Human Gene Mutation Database (HGMD®): 2003 update

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