Enzymatically crosslinked gelatin–laminin hydrogels for applications in neuromuscular tissue engineering

Author:

Besser Rachel R.1234,Bowles Annie C.1234,Alassaf Ahmad12345,Carbonero Daniel1234,Claure Isabella1234,Jones Ellery1234,Reda Joseph1234,Wubker Laura1234,Batchelor Wyndham1234,Ziebarth Noël1234,Silvera Risset6784,Khan Aisha67849,Maciel Renata10784,Saporta Mario10784,Agarwal Ashutosh1234ORCID

Affiliation:

1. Department of Biomedical Engineering

2. University of Miami

3. Coral Gables

4. USA

5. Department of Medical Equipment Technology

6. Miami Project to Cure Paralysis

7. University of Miami Miller School of Medicine

8. Miami

9. Interdisciplinary Stem Cell Institute

10. Department of Neurology

Abstract

We report a water-soluble and non-toxic method to incorporate additional extracellular matrix proteins into gelatin hydrogels, while obviating the use of chemical crosslinkers such as glutaraldehyde.

Funder

Charcot-Marie-Tooth Association

National Cancer Institute

National Center for Advancing Translational Sciences

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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