Neutral DNA–avidin nanoparticles as ultrasensitive reporters in immuno-PCR-Reference-Cited by-同舟云学术

Neutral DNA–avidin nanoparticles as ultrasensitive reporters in immuno-PCR

Published:2020 Issue:14 Volume:145 Page:4942-4949
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Chavan Dimple¹²³⁴^ORCID,Chen Hui¹²³⁴,Crum Mary⁵²³⁴,Vu Binh⁵²³⁴,Safari Mohammad⁵²³⁴,Smith Maxwell⁵²³⁴,Vekilov Peter⁵²³⁴,Conrad Jacinta C.⁵²³⁴^ORCID,Kourentzi Katerina⁵²³⁴^ORCID,Willson Richard C.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Biology and Biochemistry

2. University of Houston

3. Houston

4. USA

5. Department of Chemical and Biomolecular Engineering

Abstract

We have demonstrated a novel immuno-PCR-based diagnostic platform which uses self-assembled ultra-detectable DNA–avidin nanoparticles stabilized with poly(ethylene glycol) for the ultrasensitive detection of protein analytes.

Funder

National Institute of Allergy and Infectious Diseases

National Science Foundation

Cancer Prevention and Research Institute of Texas

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/AN/D0AN00134A

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