Ir/f-Ampha complex catalyzed asymmetric sequential hydrogenation of enones: a general access to chiral alcohols with two contiguous chiral centers-Reference-Cited by-同舟云学术

Ir/f-Ampha complex catalyzed asymmetric sequential hydrogenation of enones: a general access to chiral alcohols with two contiguous chiral centers

Published:2022 Issue:6 Volume:13 Page:1808-1814
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Li Wendian¹²,Yang Tilong³^ORCID,Song Nan¹,Li Ruihao¹,Long Jiao¹,He Lin⁴^ORCID,Zhang Xumu³,Lv Hui¹^ORCID

Affiliation:

1. Sauvage Center for Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Engineering Research Center of Organosilicon Compounds & Materials, Ministry of Education, Hubei Key Lab on Organic and Polymeric Optoelectronic Materials, Wuhan University, Wuhan, Hubei 430072, China

2. China Tobacco Sichuan Industrial Company, Ltd., Chengdu, Sichuan, 610065, China

3. Department of Chemistry, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, P. R. China

4. Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering, Shihezi University, Xinjiang Uygur Autonomous Region, 832000, China

Abstract

A general and efficient method for asymmetric sequential hydrogenation of α,β-unsaturated ketones has been developed. A dynamic kinetic resolution and an outer sphere pathway were involved in this transformation.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D1SC05963G

Reference63 articles.

1. Developing Chiral Ligands for Asymmetric Hydrogenation

2. Transition Metal-Catalyzed Enantioselective Hydrogenation of Enamines and Imines

3. Asymmetric Hydrogenation of Heteroarenes and Arenes