Simultaneous and sensitive determination of the main metabolites of the plasticizer DEHP and its substitutes DEHTP, DINCH and TEHTM in human urine by coupling of on-line SPE, UHPLC and tandem mass spectrometry-Reference-Cited by-同舟云学术

Simultaneous and sensitive determination of the main metabolites of the plasticizer DEHP and its substitutes DEHTP, DINCH and TEHTM in human urine by coupling of on-line SPE, UHPLC and tandem mass spectrometry

Published:2022 Issue:40 Volume:14 Page:3970-3981
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Kuhlmann Laura¹^ORCID,Münch Frank²^ORCID,Göen Thomas¹^ORCID,Eckert Elisabeth¹^ORCID

Affiliation:

1. Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friedrich-Alexander-Universität Erlangen-Nuremberg, Henkestr. 9-11, 91054 Erlangen, Germany

2. Department of Pediatric Cardiac Surgery, University Hospital Erlangen, University of Erlangen-Nuremberg, Germany

Abstract

On-line SPE-LC-MS/MS method for the simultaneous determination of the most relevant urinary biomarkers of exposure to DEHP and the alternative plasticizers DINCH, DEHTP and TEHTM.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AY/D2AY01293F

Reference58 articles.

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2. Exposure to phthalates: Reproductive outcome and children health. A review of epidemiological studies

3. Plasticizers: negative impacts on the thyroid hormone system

4. Associations of prepubertal urinary phthalate metabolite concentrations with pubertal onset among a longitudinal cohort of boys

5. Environmental Aspects of PVC, A5-0002/200, European Parliament resolution on the Commission Green Paper (COM(2000) 469-C5-0633.2000–2000/2297 (COS)), 2001

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