Switching transcription with bacterial RNA polymerase through photocaging, photorelease and phosphorylation reactions in the major groove of DNA-Reference-Cited by-同舟云学术

Switching transcription with bacterial RNA polymerase through photocaging, photorelease and phosphorylation reactions in the major groove of DNA

Published:2019 Issue:14 Volume:10 Page:3937-3942
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Vaníková Zuzana¹²³⁴⁵,Janoušková Martina⁶⁷²⁸⁴^ORCID,Kambová Milada⁶⁷²⁸⁴,Krásný Libor⁶⁷²⁸⁴^ORCID,Hocek Michal¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Organic Chemistry and Biochemistry

2. Czech Academy of Sciences

3. 16610 Prague 6

4. Czech Republic

5. Department of Organic Chemistry

6. Dept. of Molecular Genetics of Bacteria

7. Institute of Microbiology

8. CZ-14220 Prague 4

Abstract

Biomimetic switching of in vitro transcription was developed by photochemical deprotection of photocaged 5hmU or 5hmC in template DNA (ON) and by enzymatic phosphorylation (OFF).

Funder

Grantová Agentura České Republiky

Akademie Věd České Republiky

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC00205G

Reference55 articles.

1. Nucleic Acid Modifications in Regulation of Gene Expression

2. TET Family Proteins: Oxidation Activity, Interacting Molecules, and Functions in Diseases

3. Non-canonical Bases in the Genome: The Regulatory Information Layer in DNA

4. Dynamic DNA methylation: In the right place at the right time

5. Mapping and elucidating the function of modified bases in DNA

Cited by 40 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Reversible Control of Gene Expression by Guest-Modified Adenosines in a Cell-Free System via Host–Guest Interaction;Journal of the American Chemical Society;2024-06-28

2. A direct synthesis of 5-azidomethyl pyrimidine nucleosides via dehydroxyazidation;Tetrahedron Letters;2024-06

3. Preparation of 5‐Hydroxymethyl‐pyrimidine Based Nucleosides: A Reinvestigation;European Journal of Organic Chemistry;2023-06-23

4. Sequence-independent, site-specific incorporation of chemical modifications to generate light-activated plasmids;2023-05-26

5. Precise, Orthogonal Remote-Control of Cell-Free Systems Using Photocaged Nucleic Acids;Journal of the American Chemical Society;2023-04-19