Oxidant free synthesis of α-pyrones <i>via</i> an NHC-catalyzed [3 + 3] annulation of bromoenals with 2-chloro-1,3-diketones-Reference-Cited by-同舟云学术

Oxidant free synthesis of α-pyrones via an NHC-catalyzed [3 + 3] annulation of bromoenals with 2-chloro-1,3-diketones

Published:2022 Issue:47 Volume:20 Page:9298-9301
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Luo Cong¹,Xu Xinyi¹,Xu Jianfeng²^ORCID,Chen Xingkuan¹^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Department of Chemistry, Jinan University, Guangzhou 510632, China

2. Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou 310018, China

Abstract

An efficient protocol for the synthesis of 4,5,6-trisubstituted α-pyrones was developed via an NHC-catalyzed [3 + 3] annulation between α-bromo enals and 2-chloro-1,3-diketones under oxidant-free conditions.

Funder

Fundamental Research Funds for the Central Universities

Scientific and Technological Planning Project of Guangzhou City

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB01859D

Reference44 articles.

1. Microbial pyran-2-ones and dihydropyran-2-ones