Catalytic asymmetric functionalization and dearomatization of thiophenes-Reference-Cited by-同舟云学术

Catalytic asymmetric functionalization and dearomatization of thiophenes

Published:2024 Issue:35 Volume:15 Page:14295-14303
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Zhao Zhengxing¹,Li Yingxin¹,Jia Shiqi²,Peng Lei¹³,Zhang Zian¹,Wu Fengdi¹,Wang Pengfei¹,Qin Wenling¹^ORCID,Lan Yu²⁴^ORCID,Yan Hailong¹^ORCID

Affiliation:

1. Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, P. R. China

2. Green Catalysis Center, College of Chemistry, Zhengzhou University, Zhengzhou 450001, P. R. China

3. Chongqing University FuLing Hospital, Chongqing University, Chongqing 408000, P. R. China

4. School of Chemistry and Chemical Engineering, Chongqing Key Laboratory of Theoretical and Computational Chemistry, Chongqing University, Chongqing 400030, P. R. China

Abstract

In this study, we developed an efficient strategy for the asymmetric intramolecular reactions of VQMs and thiophenes, which proceed via two exclusive pathways, yielding axially chiral thiophene derivatives characterized by high stereoselectivity.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Chongqing Municipality

Postdoctoral Research Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SC/D4SC03530E

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