Enhancers of amyloid aggregation: novel ferrocene-based compounds selective toward amyloid models-Reference-Cited by-同舟云学术

Enhancers of amyloid aggregation: novel ferrocene-based compounds selective toward amyloid models

Published:2024 Issue: Volume: Page:
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

La Manna Sara¹,Di Natale Concetta²,Panzetta Valeria²³^ORCID,Netti Paolo Antonio²³,Merlino Antonello⁴^ORCID,Kowalski Konrad⁵^ORCID,Marasco Daniela¹^ORCID

Affiliation:

1. Department of Pharmacy, University of Naples Federico II, 80131, Naples, Italy

2. Department of Ingegneria Chimica del Materiali e della Produzione Industriale (DICMAPI), University of Naples Federico II, 80125, Naples, Italy

3. Interdisciplinary Research Centre on Biomaterials (CRIB), University of Naples Federico II, Istituto Italiano di Tecnologia, 80125, Naples, Italy

4. Department of Chemical Sciences, University of Naples Federico II, 80126, Naples, Italy

5. University of Łódź, Faculty of Chemistry, Department of Organic Chemistry, Tamka 12, 91-403 Łódź, Poland

Abstract

Two ferrocene metal complexes containing propen-thymines as ligands have been shown to be selective modulators of the Aβ21–40 amyloid aggregation and may be conceived as a future class of therapeutic agents in the early stages of amylogenesis.

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QI/D4QI01854K

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