Design and in vitro/in vivo evaluations of a multiple-drug-containing gingiva disc for periodontotherapy

Author:

Jain Pooja12345,Mirza Mohd. Aamir12345,Talegaonkar Sushama16785,Nandy Shyamasree91085,Dudeja Mridu91085,Sharma Nilima1112385,Anwer Md. Khalid113141516,Alshahrani Saad M.113141516,Iqbal Zeenat12345ORCID

Affiliation:

1. Department of Pharmaceutics

2. School of Pharmaceutical Education and Research

3. Jamia Hamdard

4. New Delhi 110062

5. India

6. Delhi Pharmaceutical Sciences and Research University

7. Govt. of NCT of Delhi

8. New Delhi

9. Department of Microbiology

10. Hamdard Institute of Medical Sciences and Research

11. Department of Dentistry

12. Hamdard Institute of Medical Sciences and Research & HAH Centenary Hospital

13. College of Pharmacy

14. Prince Sattam Bin Abdulaziz University

15. Al-kharj

16. Saudi Arabia

Abstract

A gingiva disc of cellulose acetate phthalate and poloxaner F-127 was developed for the simultaneous delivery of multiple drugs, including minocycline, to promote alveolar bone regeneration by abolishing infection, impeding inflammation and averting collagen destruction.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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