Fast, highly enantioselective, and sustainable fluorination of 4-substituted pyrazolones catalyzed by amide-based phase-transfer catalysts-Reference-Cited by-同舟云学术

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Fast, highly enantioselective, and sustainable fluorination of 4-substituted pyrazolones catalyzed by amide-based phase-transfer catalysts

Published:2023 Issue:9 Volume:10 Page:2226-2233
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Wang Yakun¹^ORCID,Wang Shuaifei¹,Wu Yufeng²^ORCID,Zhao Ting³,Liu Jie¹,Zheng Junlin¹,Wang Lin¹,Lv Jieli¹,Zhang Tao¹

Affiliation:

1. School of Pharmacy, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China

2. School of Chemical Engineering, Dalian University of Technology, Dalian, Liaoning 116024, P.R. China

3. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning 117004, P.R. China

Abstract

Highly enantioselective and sustainable fluorination of 4-substituted pyrazolones has been developed by amide-based phase-transfer catalysts.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D3QO00269A

Reference61 articles.

1. Applications of Fluorine in Medicinal Chemistry

2. Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

3. Where Does the Fluorine Come From? A Review on the Challenges Associated with the Synthesis of Organofluorine Compounds

4. Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

5. Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

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