Cu-catalysed three-component C–H trifluoroalkylation of glycine derivatives: access to diverse CF<sub>3</sub>-containing amino acids-Reference-Cited by-同舟云学术

Cu-catalysed three-component C–H trifluoroalkylation of glycine derivatives: access to diverse CF₃-containing amino acids

Published:2023 Issue:9 Volume:10 Page:2301-2309
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Li Yadong¹,Lu Dengfu¹²^ORCID,Gong Yuefa¹^ORCID

Affiliation:

1. Hubei Key Laboratory of Bioinorganic Chemistry & Materia Medica, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Rd., Wuhan, Hubei, 430074, China

2. Research Institute of Huazhong University of Science and Technology in Shenzhen, 9 Yuexing 3rd Rd., Shenzhen, Guangdong, 518063, China

Abstract

A Cu-catalysed and ligand-controlled glycine ligation method is developed for the modular and selective synthesis of diverse CF3-containing amino acids and dipeptides.

Funder

Science, Technology and Innovation Commission of Shenzhen Municipality

Hubei Technological Innovation Special Fund

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D3QO00267E

Reference86 articles.

1. Advances in Chemical Protein Modification