Quantitative determination of voriconazole by thionine reduction and its potential application in a pharmaceutical and clinical setting-Reference-Cited by-同舟云学术

Quantitative determination of voriconazole by thionine reduction and its potential application in a pharmaceutical and clinical setting

Published:2023 Issue:9 Volume:15 Page:1230-1240
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Ladetto María Florencia¹²^ORCID,Lázaro-Martínez Juan Manuel³^ORCID,Devoto Tomás Brito²^ORCID,Briceño Víctor J.²⁴,Castro Guillermo R.⁵⁶^ORCID,Cuestas María Luján²^ORCID

Affiliation:

1. Departamento de Química, Laboratorio de Nanobiomateriales, Facultad de Ciencias Exactas, Centro de Investigación y Desarrollo en Fermentaciones Industriales (CINDEFI), Universidad Nacional de La Plata (UNLP) – CONICET (CCT La Plata), Calle 47 y 115, La Plata, B1900AJI, Buenos Aires, Argentina

2. Institute for Research in Microbiology and Medical Parasitology (IMPaM), University of Buenos Aires, CONICET, Buenos Aires, Argentina

3. Departamento de Ciencias Químicas, Facultad de Farmacia y Bioquímica, Instituto de Química y Metabolismo del Fármaco (IQUIMEFA UBA-CONICET), Universidad de Buenos Aires, Argentina

4. Institute of Nanobiotechnology (Nanobiotec), University of Buenos Aires, CONICET, Buenos Aires, Argentina

5. Max Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR, UNR-MPIbpC), Partner Laboratory of the Max Planck Institute for Biophysical Chemistry (MPIbpC, MPG), Centro de Estudios Interdisciplinarios (CEI) – CONICET, Universidad Nacional de Rosario, Maipú 1065, Rosario, S2000, Santa Fe, Argentina

6. Nanomedicine Research Unit (Nanomed), Center for Natural and Human Sciences (CCNH), Universidade Federal do ABC (UFABC), Santo André, SP, Brazil

Abstract

Quantification of voriconazole (VCZ) by visible spectrophotometry based on the VCZ-induced reduction of thionine (red) to leucothionine (colorless) under alkaline conditions.

Funder

Fondo para la Investigación Científica y Tecnológica

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/AY/D2AY01431A

Reference36 articles.

1. Immune defence to invasive fungal infections: A comprehensive review

2. Impact of Intravenous Administration of Voriconazole in Critically Ill Patients with Impaired Renal Function

3. Pharmacokinetic/Pharmacodynamic Profile of Voriconazole

4. 1H and 19F NMR in drug stress testing: the case of voriconazole

5. Development and validation of an efficient HPLC method for quantification of voriconazole in plasma and microdialysate reflecting an important target site

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