Enantiomers of tetrahedral metal–organic cages: a new class of highly efficient G-quadruplex ligands with potential anticancer activities-Reference-Cited by-同舟云学术

Enantiomers of tetrahedral metal–organic cages: a new class of highly efficient G-quadruplex ligands with potential anticancer activities

Published:2016 Issue:67 Volume:52 Page:10261-10264
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Xi Sai-Fei¹²³⁴⁵,Bao Ling-Yu¹²³⁴⁵,Lin Jian-Guo⁶⁷⁸⁹¹⁰,Liu Qing-Zhu⁶⁷⁸⁹¹⁰,Qiu Ling⁶⁷⁸⁹¹⁰,Zhang Feng-Li¹²³⁴⁵,Wang Yu-Xia¹²³⁴⁵,Ding Zheng-Dong¹²³⁴⁵,Li Ke⁶⁷⁸⁹¹⁰,Gu Zhi-Guo¹²³⁴⁵

Affiliation:

1. The Key Laboratory of Food Colloids and Biotechnology

2. Ministry of Education

3. School of Chemical and Material Engineering

4. Jiangnan University

5. Wuxi 214122

6. Key Laboratory of Nuclear Medicine

7. Ministry of Health

8. Jiangsu Key Laboratory of Molecular Nuclear Medicine

9. Jiangsu Institute of Nuclear Medicine

10. Wuxi 214063

Abstract

A new class of chiral tetrahedral cages efficiently stabilized antiparallel G-quadruplex DNA with moderate enantioselectivity and displayed promising cytotoxicity against several cancer cell lines.

Funder

National Natural Science Foundation of Jiangsu Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC05743H

Reference34 articles.

1. G-quadruplex DNA: A target for drug design

2. Telomere maintenance as a target for anticancer drug discovery

3. G-quadruplexes and their regulatory roles in biology

4. G-quadruplex DNA: a potential target for anti-cancer drug design

5. G-quadruplex nucleic acids as therapeutic targets

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