Fusogenic liposome-coated nanoparticles for rapid internalization into donor corneal endothelial tissue to enable prophylaxis before transplantation

Author:

M. Y. Thanuja1,Tellakula Suraksha S.1,Suryavanshi Samarth V.1,G. S. Keerthana1,Vasudev S. Chandan1,Ranganath Sudhir H.1ORCID

Affiliation:

1. Bio-INvENT Lab, Department of Chemical Engineering, Siddaganga Institute of Technology, B. H. Road, Tumakuru 572103, India

Abstract

Fusogenic liposome-coated nanoparticles rapidly internalize into ex vivo donor corneal endothelium within 3 hours of incubation at physiological temperature possibly via the non-endocytic, membrane fusion mechanism. Scale bar is 10 μm

Funder

Association for Research in Vision and Ophthalmology

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

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