Synergistic immunomodulatory effect in macrophages mediated by magnetic nanoparticles modified with miRNAs-Reference-Cited by-同舟云学术

Synergistic immunomodulatory effect in macrophages mediated by magnetic nanoparticles modified with miRNAs

Published:2022 Issue:31 Volume:14 Page:11129-11138
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Lafuente-Gómez Nuria¹^ORCID,Wang Shiqi²^ORCID,Fontana Flavia²,Dhanjani Mónica¹,García-Soriano David¹,Correia Alexandra²,Castellanos Milagros¹,Rodriguez Diaz Ciro¹^ORCID,Salas Gorka¹³^ORCID,Santos Hélder A.²⁴^ORCID,Somoza Álvaro¹³^ORCID

Affiliation:

1. Instituto Madrileño de Estudios Avanzados en Nanociencia (IMDEA Nanociencia), 28049, Madrid, Spain

2. Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, FI-00014 Helsinki, Finland

3. Unidad de Nanobiotecnología Asociada al Centro Nacional de Biotecnología (CSIC), 28049, Madrid, Spain

4. Department of Biomedical Engineering, W.J. Kolff Institute for Biomedical Engineering and Materials Science, University Medical Center Groningen/University of Groningen, Ant. Deusinglaan 1, 9713 AV Groningen, The Netherlands

Abstract

The interactions of magnetic nanoparticles with blood components must be carefully assessed to select nanoparticles for biomedical applications. Remarkably, MNP's surface can be tuned to add and enhance immunomodulatory properties in macrophages.

Funder

Academy of Finland

Sigrid Juséliuksen Säätiö

Ministerio de Ciencia y Tecnología

Horizon 2020 Framework Programme

Ministerio de Economía y Competitividad

Comunidad de Madrid

Ministerio de Educación y Cultura

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science