Proteomic analysis of exosomes derived from human mature milk and colostrum of mothers with term, late preterm, or very preterm delivery

Author:

Freiría-Martínez Luis12,Iglesias-Martínez-Almeida Marta12ORCID,Rodríguez-Jamardo Cynthia12,Rivera-Baltanás Tania13,Comís-Tuche María1,Rodrígues-Amorím Daniela14,Fernández-Palleiro Patricia1,Blanco-Formoso María5,Álvarez-Chaver Paula6ORCID,Diz-Chaves Yolanda7,Gonzalez-Freiria Natalia8,Martín-Forero-Maestre Montserrat9,Fernández-Feijoo Cristina Durán10,Suárez-Albo María8ORCID,Fernández-Lorenzo Jose Ramón8,Guisán Ana Concheiro8ORCID,Olivares Jose Manuel13,Spuch Carlos13ORCID

Affiliation:

1. Translational Neuroscience Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, Vigo, 36312, Spain

2. University of Vigo, Vigo, 36310, Spain

3. CIBERSAM, Madrid, 28029, Spain

4. Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA

5. Department of Physical Chemistry, Singular Center for Biomedical Research (CINBIO), Universidade de Vigo, Vigo, 36310, Spain

6. Structural Determination, Proteomic and Genomic Service, CACTI, University of Vigo, Vigo, Spain

7. Laboratory of Endocrinology, Singular Center for Biomedical Research (CINBIO), Universidade de Vigo, 36310 Vigo, Spain

8. Neonatal Intensive Care Unit, Alvaro Cunqueiro Hospital, Vigo, 36312, Spain

9. Human Milk Bank of Vigo, Alvaro Cunqueiro Hospital, Vigo, 36312, Spain

10. Neonatology Unit of the University Hospital of Santiago de Compostela (CHUS), Santiago de Compo-stela, 15706, Spain

Abstract

The growth and development of the human brain is a long and complex process that requires a precise sequence of genetic and molecular events.

Funder

Instituto de Salud Carlos III

Axencia Galega de Innovación

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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