Nanoscale insight into the degradation mechanisms of the cartilage articulating surface preceding OA-Reference-Cited by-同舟云学术

Nanoscale insight into the degradation mechanisms of the cartilage articulating surface preceding OA

Published:2020 Issue:14 Volume:8 Page:3944-3955
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Shoaib Tooba¹²³⁴^ORCID,Yuh Catherine⁵⁶⁷⁴^ORCID,Wimmer Markus A.⁵⁶⁷⁴^ORCID,Schmid Thomas M.⁵⁶⁷⁴,Espinosa-Marzal Rosa M.¹²³⁴⁸^ORCID

Affiliation:

1. Materials Science and Engineering

2. University of Illinois at Urbana-Champaign

3. Urbana

4. USA

5. Department of Orthopedics

6. Rush University Medical Center

7. Chicago

8. Civil and Environmental Engineering Department

Abstract

Osteoarthritis (OA) is a degenerative disease and leading cause of disability globally. We report the a fundamental study of the mechanisms underlying deterioration of hydrated cartilage in the presence of elevated calcium content preceding OA.

Funder

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/BM/D0BM00496K

Reference70 articles.

1. Structure of the most superficial layer of articular cartilage

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