Ultra-high photoactive thiadiazolo[3,4-g]quinoxaline nanoparticles with active-targeting capability for deep photodynamic therapy

Author:

Zhang Li-Peng1,Li Xianqiang12,Zhao Hongyou3,Kang Lin12,Liu Shiyang12,Liu Tianlong4ORCID,Zhao Yuxia12ORCID

Affiliation:

1. Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 Zhongguancun East Road, Haidian District, Beijing, 100190, P. R. China

2. University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing, 100049, P. R. China

3. Institute of Engineering Medicine, Beijing Institute of Technology, No. 5, South Street, Zhongguancun, Haidian District, Beijing, 100081, P. R. China

4. Laboratory of Veterinary Pathology and Nanopathology, College of Veterinary Medicine, China Agricultural University, No. 2 West Road Yuanmingyuan, Beijing, 100193, P. R. China

Abstract

A novel biocompatible photosensitizer (TQs-PEG4) with an ultra-high singlet oxygen quantum yield was designed and synthesized for a deep photodynamic therapy under 660 nm laser irradiation.

Funder

Natural Science Foundation of Beijing Municipality

National Natural Science Foundation of China

Beijing Institute of Technology

China Agricultural University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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