Enantiopure synthesis of 7-(1-pyrindanyl)propargyl ethers as rasagiline analogues via chemical or enzymatic resolution of 1-pyrindan-7-ol-Reference-Cited by-同舟云学术

Enantiopure synthesis of 7-(1-pyrindanyl)propargyl ethers as rasagiline analogues via chemical or enzymatic resolution of 1-pyrindan-7-ol

Published:2015 Issue:126 Volume:5 Page:104509-104515
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sousa Carlos A. D.¹²³⁴,Sampaio-Dias Ivo E.⁵²³⁴,Rizzo-Aguiar Fabio⁵²³⁴,Garcia-Mera Xerardo⁶⁷⁸⁹¹⁰,Rodríguez-Borges José E.⁵²³⁴

Affiliation:

1. REQUIMTE/LAQV

2. Departamento de Química e Bioquímica da Universidade do Porto

3. 4169-007 Porto

4. Portugal

5. REQUIMTE/UCIBIO

6. Departamento de Química Orgánica

7. Facultade de Farmacia

8. Universidade de Santiago de Compostela

9. E-15782 Santiago de Compostela

10. Spain

Abstract

Enantiopure 7-(1-pyrindanyl)propargyl ethers – rasagiline analogues – were efficiently obtainedviachemical and/or enzymatic resolution of the racemic precursor 1-pyrindan-7-ol.

Funder

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA24868J

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